Source:http://linkedlifedata.com/resource/pubmed/id/11867080
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2002-2-27
|
| pubmed:abstractText |
For cDNA array methods that depend on imaging of a radiolabel, we show that bleedover of one spot onto another, due to the gap between the array and the imaging media, can be a major problem. The images can be sharpened, however, using a blind convolution method based on the EM algorithm. The sharpened images look like a set of donuts, which concurs with our knowledge of the spotting process. Oversharpened images are actually useful as well, in locating the centers of each spot.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0025-5564
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
176
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1-15
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:11867080-Algorithms,
pubmed-meshheading:11867080-DNA, Complementary,
pubmed-meshheading:11867080-Gene Expression Profiling,
pubmed-meshheading:11867080-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11867080-Humans,
pubmed-meshheading:11867080-Image Processing, Computer-Assisted,
pubmed-meshheading:11867080-Multiple Myeloma,
pubmed-meshheading:11867080-Oligonucleotide Array Sequence Analysis
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Sharpening spots: correcting for bleedover in cDNA array images.
|
| pubmed:affiliation |
Department of Health Sciences Research, Mayo Foundation, Rochester, MN 55905, USA. therneau.terry@mayo.edu
|
| pubmed:publicationType |
Journal Article
|