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11865647
Source:
http://linkedlifedata.com/resource/pubmed/id/11865647
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rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0209606
,
umls-concept:C0243077
,
umls-concept:C1292724
pubmed:issue
2
pubmed:dateCreated
2002-2-27
pubmed:abstractText
A combinatorial approach towards identifying inhibitors of VALA-4 was investigated. A library of piperazine-peptoid-bisarylureas was assembled in solid phase and screening in the novel v-well assay enabled the identification of active compounds.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9516534
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/1-hydroxybenzotriazole
,
http://linkedlifedata.com/resource/pubmed/chemical/Dimethyl Sulfoxide
,
http://linkedlifedata.com/resource/pubmed/chemical/Dimethylformamide
,
http://linkedlifedata.com/resource/pubmed/chemical/Integrin alpha4beta1
,
http://linkedlifedata.com/resource/pubmed/chemical/Integrins
,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Library
,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides
,
http://linkedlifedata.com/resource/pubmed/chemical/Peptoids
,
http://linkedlifedata.com/resource/pubmed/chemical/Piperazines
,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Lymphocyte Homing
,
http://linkedlifedata.com/resource/pubmed/chemical/Triazoles
,
http://linkedlifedata.com/resource/pubmed/chemical/piperazine
pubmed:status
MEDLINE
pubmed:issn
1381-1991
pubmed:author
pubmed-author:HugoRR
,
pubmed-author:LakePP
,
pubmed-author:LewisII
,
pubmed-author:MaidaSS
,
pubmed-author:MengusMM
,
pubmed-author:RohdeBB
,
pubmed-author:WeetallMM
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-73
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:11865647-Chromatography, High Pressure Liquid
,
pubmed-meshheading:11865647-Combinatorial Chemistry Techniques
,
pubmed-meshheading:11865647-Databases as Topic
,
pubmed-meshheading:11865647-Dimethyl Sulfoxide
,
pubmed-meshheading:11865647-Dimethylformamide
,
pubmed-meshheading:11865647-Integrin alpha4beta1
,
pubmed-meshheading:11865647-Integrins
,
pubmed-meshheading:11865647-Mass Spectrometry
,
pubmed-meshheading:11865647-Models, Chemical
,
pubmed-meshheading:11865647-Peptide Library
,
pubmed-meshheading:11865647-Peptides
,
pubmed-meshheading:11865647-Peptoids
,
pubmed-meshheading:11865647-Piperazines
,
pubmed-meshheading:11865647-Receptors, Lymphocyte Homing
,
pubmed-meshheading:11865647-Software
,
pubmed-meshheading:11865647-Triazoles
pubmed:year
2000
pubmed:articleTitle
Combinatorial approaches to inhibitors of VLA-4: piperazine-peptoid-bisarylureas.
pubmed:affiliation
Transplantation Research Chemistry Unit, S-507.3.03, Novartis Pharma, CH-4002 Basel, Switzerland. ian.lewis@pharma.novartis.com
pubmed:publicationType
Journal Article