11864715

Source:http://linkedlifedata.com/resource/pubmed/id/11864715

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0004927, umls-concept:C0009240, umls-concept:C0019409, umls-concept:C0026336, umls-concept:C0205486, umls-concept:C1554184, umls-concept:C1704259, umls-concept:C1705987
pubmed:issue	1-2
pubmed:dateCreated	2002-2-26
pubmed:abstractText	Psychological accounts have characterised attention-deficit/hyperactivity disorder (AD/HD) as either a neuro-cognitive disorder of regulation or a motivational style. Poor inhibitory control is thought to underpin AD/HD children's dysregulation while delay aversion is a dominant characteristic of their motivational style. A recent 'head to head' study of these two accounts suggest that delay aversion and poor inhibitory control are independent co-existing characteristics of AD/HD (combined type). In the present paper we build on these findings to propose a dual pathway model of AD/HD that recognises two quite distinct sub-types of the disorder. In one AD/HD is the result of the dysregulation of action and thought resulting from poor inhibitory control associated with the meso-cortical branch of the dopamine system projecting in the cortical control centres (e.g. pre-frontal cortex). In the other AD/HD is a motivational style characterised by an altered delay of reward gradient linked to the meso-limbic dopamine branch associated with the reward circuits (e.g. nucleus accumbens). The two pathways are further distinguished at the levels of symptoms, cognitive and motivation profiles and genetic and non-genetic origins.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8004872
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0166-4328
pubmed:author	pubmed-author:Sonuga-BarkeEdmund J SEJ
pubmed:issnType	Print
pubmed:day	10
pubmed:volume	130
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	29-36
pubmed:dateRevised	2006-3-1
pubmed:meshHeading	pubmed-meshheading:11864715-Animals, pubmed-meshheading:11864715-Attention Deficit Disorder with Hyperactivity, pubmed-meshheading:11864715-Behavior, pubmed-meshheading:11864715-Cognition, pubmed-meshheading:11864715-Humans
pubmed:year	2002
pubmed:articleTitle	Psychological heterogeneity in AD/HD--a dual pathway model of behaviour and cognition.
pubmed:affiliation	Centre for Research into Psychological Development, Department of Psychology, University of Southampton, SO17 1BJ, UK. ejb3@soton.ac.uk
pubmed:publicationType	Journal Article, Review