Linked Life Data

11862666

Source:http://linkedlifedata.com/resource/pubmed/id/11862666

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-2-26
pubmed:abstractText
The aim of the present study was to investigate the functional changes in the sympathetic nerves in the rat myometrium during pregnancy by electric field stimulation (EFS) in vitro. In our experiments the contractility of the rat myometrium were registered at 5, 10, 15, 18, 20, 22 (term) day of pregnancy, in non pregnant rats and in 6-OH-dopamine pretreated rats. The parameters of EFS were the following: pulse width 0.6 ms, frequency range of nerve stimulation 1-70 Hz, supramaximal voltage 40 V. We concluded that low pulse width and low frequency stimulation is selective for adrenergic nerves. We found that during pregnancy a gradual drop-out of low frequency induced uterine smooth muscle contraction appears. It is surprising that very low frequency stimulation has no effect on the 5th day of pregnancy although the same frequency stimulation causes contraction on the 10th day. By the 22nd day of pregnancy the rat uterus shows the same responsiveness to nerve stimulation as it is detected in 6-OH-dopamine pretreated non pregnant rats. The adrenergic denervation of the pregnant uterus does not mean that it loses the ability to respond to cathecholamines since non-synaptic adrenergic receptors exist in the late pregnant rat uterus.
pubmed:language
hun
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0001-6659
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
[Influence of adrenergic denervation on uterine contractility of pregnant rats in vitro].
pubmed:affiliation
Szegedi Tudományegyetem, Gyógyszerhatástani és Biofarmáciai Intézet, 6720 Szeged, Eötvös u. 6.
pubmed:publicationType
Journal Article, English Abstract