Linked Life Data

11861160

Source:http://linkedlifedata.com/resource/pubmed/id/11861160

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-2-25
pubmed:abstractText
The adult mammalian neocortex, the major region of the cerebral cortex, is divided into functionally specialized areas, defined by distinct architecture and axonal connections. Extrinsic influences, such as thalamocortical input, and genetic regulation, intrinsic to the dorsal telencephalon, control the gradual emergence of area-specific properties during development. Major recent advances in this field include: the first demonstration of the genetic regulation of arealization, implicating the transcription factors Emx2 and Pax6 in the direct control of area identities; and the demonstration of the potential role of the signaling protein, fibroblast growth factor 8, in the early patterning of arealization genes, such as Emx2.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0959-4388
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
14-25
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Patterning centers, regulatory genes and extrinsic mechanisms controlling arealization of the neocortex.
pubmed:affiliation
Molecular Neurobiology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, California 96037, USA. doleary@salk.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review