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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2002-2-25
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pubmed:abstractText |
Protein tyrosine phosphatase gamma (PTPgamma) has been implicated as a tumor suppressor gene in kidney and lung cancers. Our previous results indicate that estradiol-17beta (E2)-induced suppression of PTPgamma may play a role in mammary tumorigenesis. Zeranol (Z), a nonsteroidal growth promoter with estrogenic activity that is used by the US meat industry, induces estrogenic responses in primary cultured breast cells and breast cancer cell lines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Estrogens, Non-Steroidal,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PTPRG protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Tyrosine Phosphatases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor-Like Protein Tyrosine...,
http://linkedlifedata.com/resource/pubmed/chemical/Zeranol
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0167-6806
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-35
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11859871-Breast,
pubmed-meshheading:11859871-Breast Neoplasms,
pubmed-meshheading:11859871-Cell Communication,
pubmed-meshheading:11859871-Cell Transformation, Neoplastic,
pubmed-meshheading:11859871-Epithelium,
pubmed-meshheading:11859871-Estradiol,
pubmed-meshheading:11859871-Estrogens, Non-Steroidal,
pubmed-meshheading:11859871-Female,
pubmed-meshheading:11859871-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11859871-Humans,
pubmed-meshheading:11859871-Immunohistochemistry,
pubmed-meshheading:11859871-Nerve Tissue Proteins,
pubmed-meshheading:11859871-Protein Tyrosine Phosphatases,
pubmed-meshheading:11859871-RNA, Messenger,
pubmed-meshheading:11859871-Receptor-Like Protein Tyrosine Phosphatases, Class 5,
pubmed-meshheading:11859871-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11859871-Stromal Cells,
pubmed-meshheading:11859871-Tumor Cells, Cultured,
pubmed-meshheading:11859871-Zeranol
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pubmed:year |
2002
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pubmed:articleTitle |
Involvement of breast epithelial-stromal interactions in the regulation of protein tyrosine phosphatase-gamma (PTPgamma) mRNA expression by estrogenically active agents.
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pubmed:affiliation |
Laboratory of Reproductive and Molecular Endocrinology, College of Veterinary Medicine, The Ohio State University, Columbus 43210-1092, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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