Source:http://linkedlifedata.com/resource/pubmed/id/11857318
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2002-2-21
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| pubmed:abstractText |
Barrett esophagus (BE)/Barrett adenocarcinoma and distal gastric intestinal metaplasia (IM)/adenocarcinoma are similar histologically, but they differ in their clinical presentation, epidemiology, and pathogenesis. Differentiating BE from gastric IM and Barrett adenocarcinoma from gastric adenocarcinoma is difficult, especially when IM is short or tumors are large and involve both sides of the esophagogastric junction. Previously, the authors identified unique cytokeratin (CK) immunoreactivity patterns that were associated strongly with BE and Barrett adenocarcinoma. The specificity of CK7 and CK20 (CK7/20) expression patterns in patients with IM-associated gastric adenocarcinoma, which is distinct epidemiologically from BE/Barrett adenocarcinoma, has not been evaluated. The objective of the current study was to evaluate the CK7/20 expression patterns in noncardia, IM-associated gastric adenocarcinoma in a Chinese population with a low risk for BE and esophageal adenocarcinoma and a high risk for Helicobacter pylori infection and gastric carcinoma.
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| pubmed:grant | |
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Feb
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| pubmed:issn |
0008-543X
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2002 American Cancer Society. DOI 10.1002/cncr.10215
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| pubmed:issnType |
Print
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| pubmed:day |
1
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| pubmed:volume |
94
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
820-31
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| pubmed:dateRevised |
2007-11-14
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| pubmed:meshHeading |
pubmed-meshheading:11857318-Adenocarcinoma,
pubmed-meshheading:11857318-Aged,
pubmed-meshheading:11857318-Barrett Esophagus,
pubmed-meshheading:11857318-Biopsy,
pubmed-meshheading:11857318-Diagnosis, Differential,
pubmed-meshheading:11857318-Endoscopy,
pubmed-meshheading:11857318-Esophageal Neoplasms,
pubmed-meshheading:11857318-Female,
pubmed-meshheading:11857318-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11857318-Helicobacter Infections,
pubmed-meshheading:11857318-Humans,
pubmed-meshheading:11857318-Intermediate Filament Proteins,
pubmed-meshheading:11857318-Intestines,
pubmed-meshheading:11857318-Keratin-20,
pubmed-meshheading:11857318-Male,
pubmed-meshheading:11857318-Metaplasia,
pubmed-meshheading:11857318-Middle Aged,
pubmed-meshheading:11857318-Phenotype,
pubmed-meshheading:11857318-Risk Factors,
pubmed-meshheading:11857318-Stomach Neoplasms,
pubmed-meshheading:11857318-Tumor Markers, Biological
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| pubmed:year |
2002
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| pubmed:articleTitle |
Cytokeratin expression patterns in noncardia, intestinal metaplasia-associated gastric adenocarcinoma: implication for the evaluation of intestinal metaplasia and tumors at the esophagogastric junction.
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| pubmed:affiliation |
Department of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. shenb@ccf.org
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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