Source:http://linkedlifedata.com/resource/pubmed/id/11856582
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2002-2-21
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pubmed:abstractText |
The performance of clinical signs as a diagnostic test for the detection of classical swine fever (CSF) outbreaks during the 1997-1998 CSF epidemic in The Netherlands was evaluated by constructing and analysing a receiver operating characteristic (ROC) curve. This curve assesses the discriminating ability of a diagnostic test over a range of test signals. The cut-off values for a defined diagnostic test to detect CSF outbreaks were set by different combinations of clinical signs observed. The area under the ROC curve, which is a quantitative measure of test performance, was significantly (P<0.001) larger than the area under the random ROC curve. This indicates that clinical signs have a significantly higher performance as a diagnostic test for the detection of CSF than for flipping a coin. However, the gain in diagnostic performance compared to a random process is not as much as we would wish it to be. The optimal efficient diagnostic test combined a sensitivity of 72.7% with a specificity of 52.7%, with a combination of the following clinical signs: unsteady gait/ataxia, not eating, not reacting to antibiotic treatment, conjunctivitis, hard faecal pellets.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0378-1135
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
323-32
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:11856582-Animals,
pubmed-meshheading:11856582-Anorexia,
pubmed-meshheading:11856582-Classical Swine Fever,
pubmed-meshheading:11856582-Classical swine fever virus,
pubmed-meshheading:11856582-Disease Outbreaks,
pubmed-meshheading:11856582-Female,
pubmed-meshheading:11856582-Gait Ataxia,
pubmed-meshheading:11856582-Netherlands,
pubmed-meshheading:11856582-Questionnaires,
pubmed-meshheading:11856582-ROC Curve,
pubmed-meshheading:11856582-Sensitivity and Specificity,
pubmed-meshheading:11856582-Swine
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pubmed:year |
2002
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pubmed:articleTitle |
Quantitative assessment of clinical signs for the detection of classical swine fever outbreaks during an epidemic.
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pubmed:affiliation |
Epidemiology Unit, Animal Health Service, P.O. Box 9, 7400 AA Deventer, The Netherlands. a.elbers@gdvdieren.nl
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pubmed:publicationType |
Journal Article
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