rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2002-2-20
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pubmed:abstractText |
Vasorelaxation to endothelial NO is mediated by activation of soluble guanylyl cyclase (sGC) and impaired by hypercholesterolemia in animals and humans. We investigated whether hypercholesterolemia impacts expression and function of sGC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/6-anilino-5,8-quinolinedione,
http://linkedlifedata.com/resource/pubmed/chemical/Aminoquinolines,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Guanylate Cyclase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Donors,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents,
http://linkedlifedata.com/resource/pubmed/chemical/soluble guanylyl cyclase
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
19
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
855-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11854127-Aminoquinolines,
pubmed-meshheading:11854127-Animals,
pubmed-meshheading:11854127-Aorta,
pubmed-meshheading:11854127-Arteriosclerosis,
pubmed-meshheading:11854127-Cholesterol,
pubmed-meshheading:11854127-Diet, Atherogenic,
pubmed-meshheading:11854127-Enzyme Activation,
pubmed-meshheading:11854127-Enzyme Inhibitors,
pubmed-meshheading:11854127-Guanylate Cyclase,
pubmed-meshheading:11854127-Hypercholesterolemia,
pubmed-meshheading:11854127-Male,
pubmed-meshheading:11854127-Nitric Oxide,
pubmed-meshheading:11854127-Nitric Oxide Donors,
pubmed-meshheading:11854127-Rabbits,
pubmed-meshheading:11854127-Rats,
pubmed-meshheading:11854127-Rats, Wistar,
pubmed-meshheading:11854127-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:11854127-Signal Transduction,
pubmed-meshheading:11854127-Tunica Intima,
pubmed-meshheading:11854127-Up-Regulation,
pubmed-meshheading:11854127-Vasodilation,
pubmed-meshheading:11854127-Vasodilator Agents
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pubmed:year |
2002
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pubmed:articleTitle |
Effect of hypercholesterolemia on expression and function of vascular soluble guanylyl cyclase.
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pubmed:affiliation |
Institut für Pharmakologie und Klinische Pharmakologie, Heinrich-Heine-Universität, Düsseldorf, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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