Maternal anti-Ro and anti-La antibodies are associated with congenital heart block (CHB). Although endocardial fibroelastosis (EFE) has been described in isolated cases of autoantibody-mediated CHB, the natural history and pathogenesis of this disease are poorly understood.
Department of Paediatrics, Division of Cardiology, The Hospital for Sick Children, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.