Source:http://linkedlifedata.com/resource/pubmed/id/11844869
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2002-2-14
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pubmed:abstractText |
Apolipoprotein E (apoE) mediates lipoprotein uptake by receptors such as the LDL receptor (LDLR). The isoform apoE4 has been linked to Alzheimer's disease and to poor outcomes after brain injury. Astrocytes that induce blood brain barrier (BBB) properties in endothelium also produce apoE. We decided to investigate the role of apoE in BBB function and in the restoration of BBB after brain injury.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1076-1551
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
810-5
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pubmed:dateRevised |
2008-11-20
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pubmed:meshHeading |
pubmed-meshheading:11844869-Animals,
pubmed-meshheading:11844869-Apolipoproteins E,
pubmed-meshheading:11844869-Blood-Brain Barrier,
pubmed-meshheading:11844869-Brain Injuries,
pubmed-meshheading:11844869-Capillary Permeability,
pubmed-meshheading:11844869-Cholesterol,
pubmed-meshheading:11844869-Mice,
pubmed-meshheading:11844869-Mice, Inbred C57BL,
pubmed-meshheading:11844869-Mice, Knockout
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pubmed:year |
2001
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pubmed:articleTitle |
ApoE deficiency compromises the blood brain barrier especially after injury.
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pubmed:affiliation |
The Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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