Linked Life Data

11841620

Source:http://linkedlifedata.com/resource/pubmed/id/11841620

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Suppl
pubmed:dateCreated
2002-3-7
pubmed:abstractText
Unilateral ureteral obstruction (UUO) leads to interstitial fibrosis of the obstructed kidney, and TGF-beta is considered to play an important role in this fibrotic process. Smad7 has been recently identified as an antagonist of TGF-beta signaling. To investigate whether this novel molecule can be exploited for therapy of renal fibrosis, we determined the effect of exogenous Smad7, introduced by a recombinant adenovirus vector combined with in vivo electroporation (EP), on UUO-induced renal fibrosis in rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1523-1755
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S94-8
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Gene transfer of Smad7 using electroporation of adenovirus prevents renal fibrosis in post-obstructed kidney.
pubmed:affiliation
Homeostasis Medicine and Nephrology, Tokyo Medical and Dental University and Allergy Research Center, Juntendo University, School of Medicine, Tokyo, Japan. yteada.kid@tmd.ac.jp
pubmed:publicationType
Journal Article