Source:http://linkedlifedata.com/resource/pubmed/id/11841537
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-2-13
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pubmed:abstractText |
Hair fiber differentiation involves the expression of both hair keratin intermediate filament proteins and their associated proteins, termed keratin-associated proteins. In this study, cDNA clones encoding two novel keratin-associated proteins were isolated from human hair follicle mRNA. The predicted amino acid sequence derived from these clones revealed that these proteins represent members of the human keratin-associated protein 1 family. They show strong sequence homology to two previously described keratin-associated protein 1 family members hKAP1.1 A and hKAP1.1B. We have called these new proteins hKAP1.6 and hKAP1.7, respectively. RNA in situ hybridization studies of human anagen hair follicles using a conserved probe for these four keratin-associated protein 1 members demonstrated the expression of this group in the differentiated portions of the hair cortex.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-202X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
226-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11841537-Amino Acid Sequence,
pubmed-meshheading:11841537-Base Sequence,
pubmed-meshheading:11841537-DNA, Complementary,
pubmed-meshheading:11841537-Hair Follicle,
pubmed-meshheading:11841537-Humans,
pubmed-meshheading:11841537-In Situ Hybridization,
pubmed-meshheading:11841537-Keratins,
pubmed-meshheading:11841537-Keratins, Hair-Specific,
pubmed-meshheading:11841537-Molecular Sequence Data,
pubmed-meshheading:11841537-Sequence Homology, Amino Acid,
pubmed-meshheading:11841537-Sulfur,
pubmed-meshheading:11841537-Tissue Distribution
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pubmed:year |
2002
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pubmed:articleTitle |
hKAP1.6 and hKAP1.7, two novel human high sulfur keratin-associated proteins are expressed in the hair follicle cortex.
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pubmed:affiliation |
Department of Dermatology, Niigata University School of Medicine, Asahimachi-dori, Niigata, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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