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pubmed-article:11839636pubmed:abstractTextWe have shown that the calmodulin inhibitor W-7 suppresses torsade de pointes (TdP) without shortening the QT interval, which is consistent with other findings that QT prolongation, per se, is insufficient to generate TdP. ECGs were analyzed from a well-characterized animal model of TdP to identify more reliable predictors of this life-threatening ventricular arrhythmia.lld:pubmed
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pubmed-article:11839636pubmed:articleTitleCalmodulin inhibitor W-7 unmasks a novel electrocardiographic parameter that predicts initiation of torsade de pointes.lld:pubmed
pubmed-article:11839636pubmed:affiliationDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tenn 37232-6300, USA.lld:pubmed
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