11830393

Source:http://linkedlifedata.com/resource/pubmed/id/11830393

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0018943, umls-concept:C0020008, umls-concept:C0200627, umls-concept:C0220825
pubmed:issue	1
pubmed:dateCreated	2002-2-6
pubmed:abstractText	The Beckman Coulter HmX is an hematological analyzer designed to provide a complete hematological profile including CBC, WBC differential (diff) and reticulocyte parameters. It has been evaluated in our laboratory over a two weeks period with three purposes: (1) a technical evaluation of the HmX performance, in regard to repeatability, linearity, carry over; (2) a comparison of numerical results (CBC, WBC diff) and analytical performance (flag sensitivity and specificity) with those obtained with the Coulter MaxM in use in our laboratory; (3) an analysis of the flagging algorithms using the blood smear as the reference method. The first part of the evaluation showed that the Beckman Coulter HmX is reproducible, and linear. The comparison between MaxM and HmX showed that the results given by the two instruments are similar and suggested that the Beckman Coulter HmX could replace the current hematology analyzer in use in our laboratory. The comparison of the flag system performance, between the Beckman Coulter HmX and the Coulter MaxM, has been performed with samples from three subgroups of patients (general departments, surgery and intensive care, hematological unit), and showed that the HmX is significantly more sensitive than the MaxM, with an higher global efficiency. The comparison of predictive values also showed a better performance of the HmX. In conclusion, the Beckman Coulter HmX is suited for an use in medium sized hospital laboratories (80 to 150 CBC diff/day), with good technical and analytical performance, a throughput of 75 samples/hr and a workstation allowing data management in accord with quality assurance guidelines in France.
pubmed:language	fre
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/2984690R
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:issn	0003-3898
pubmed:author	pubmed-author:BelaouniHH, pubmed-author:Cluet-DennetièreSS, pubmed-author:DarnigeLL, pubmed-author:DelavenneJJ, pubmed-author:FourcadeCC
pubmed:issnType	Print
pubmed:volume	60
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	47-55
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11830393-Equipment Design, pubmed-meshheading:11830393-Hematologic Tests, pubmed-meshheading:11830393-Hospitals, General, pubmed-meshheading:11830393-Humans, pubmed-meshheading:11830393-Reproducibility of Results, pubmed-meshheading:11830393-Sensitivity and Specificity
pubmed:articleTitle	[Evaluation of the Beckman Coulter HmX hematology analyser at a general hospital].
pubmed:affiliation	Laboratoire de biologie, CH de Compiègne, 8, rue Henri-Adnot, ZAC de Mercières, BP 29, 60321 Compiègne cedex.
pubmed:publicationType	Journal Article, Comparative Study, English Abstract, Evaluation Studies