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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-3-6
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pubmed:abstractText |
Apoptosis is a key mechanism of reperfusion injury in the ischemic liver. The apoptotic pathway is highly regulated by anti-apoptotic factors, such as Bcl-2. We evaluated the effect of Bcl-2 overexpression on apoptosis and the activation of the apoptotic cascade after hepatic ischemia and reperfusion.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
218-25
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11830333-Animals,
pubmed-meshheading:11830333-Apoptosis,
pubmed-meshheading:11830333-Gene Expression,
pubmed-meshheading:11830333-Hepatocytes,
pubmed-meshheading:11830333-Humans,
pubmed-meshheading:11830333-Immunity, Innate,
pubmed-meshheading:11830333-In Situ Nick-End Labeling,
pubmed-meshheading:11830333-Liver,
pubmed-meshheading:11830333-Mice,
pubmed-meshheading:11830333-Mice, Inbred C57BL,
pubmed-meshheading:11830333-Mice, Transgenic,
pubmed-meshheading:11830333-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:11830333-Reperfusion Injury
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pubmed:year |
2002
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pubmed:articleTitle |
Transgenic mice overexpressing human Bcl-2 are resistant to hepatic ischemia and reperfusion.
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pubmed:affiliation |
Laboratory of Liver Transplantation and Hepatobiliary Surgery, Department of Visceral Surgery and Transplantation, University of Zürich, 8091 Zürich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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