Source:http://linkedlifedata.com/resource/pubmed/id/11826480
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2002-2-5
|
pubmed:abstractText |
A genotypic method for predicting rifampicin resistance in Mycobacterium leprae has been developed and rigorously tested on mouse footpad-derived and clinical specimens. A series of immobilized oligonucleotide capture probes can discriminate between wild type and mutant rpoB alleles, and positive controls are available for the most frequent mutation affecting Ser425. Two different non-radioactive detection formats have been tested with comparable success in both an industrialized and a developing country. The standardized procedure could now be used in a prospective study of potential rifampicin resistance among multibacillary patients.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0305-7518
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
72
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
441-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11826480-Animals,
pubmed-meshheading:11826480-Base Sequence,
pubmed-meshheading:11826480-Drug Resistance, Microbial,
pubmed-meshheading:11826480-Humans,
pubmed-meshheading:11826480-Leprostatic Agents,
pubmed-meshheading:11826480-Leprosy,
pubmed-meshheading:11826480-Mice,
pubmed-meshheading:11826480-Molecular Sequence Data,
pubmed-meshheading:11826480-Mycobacterium leprae,
pubmed-meshheading:11826480-Oligonucleotide Probes,
pubmed-meshheading:11826480-Polymerase Chain Reaction,
pubmed-meshheading:11826480-Predictive Value of Tests,
pubmed-meshheading:11826480-Rifampin
|
pubmed:year |
2001
|
pubmed:articleTitle |
A method for rapid detection of rifampicin-resistant isolates of Mycobacterium leprae.
|
pubmed:affiliation |
Unité de Génétique Moléculaire Bactérienne, Institut Pasteur, 28 Rue du Dr Roux, 75724 Paris, France.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|