Source:http://linkedlifedata.com/resource/pubmed/id/11824784
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2002-2-4
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pubmed:abstractText |
Between 1995 and 1999, several cattle of a group of 80 heifers died acutely on a pasture in the Swiss Alps. The animals were Found dead between July 9th and 15th eachyear. Only 1 animal was examined on post-mortem, and no significant lesions were found. Aconitum vulpera, A napellus, and Delphinium elatum were identified in the pasture. The presence of diterpenoid alkaloid-containing plants in the pasture, the rapid death of the animals, and the lack of pathologic lesions suggested diterpenoid alkaloid toxicosis as a cause of death. A multiresidue alkaloid screen using gas chromatography with a mass spectrometric detector was employed on rumen, abomasal, small intestine, and cecal contents from the I heifer. Deltaline, deltamine, and lycoctonine were identified. Aconitine was found in all gastrointestinal samples using a sensitive and highly specific liquid chromatography/mass spectrometry methodology for aconitine analysis. The findings ofditerpenoid alkaloids in the gastrointestinal contents confirmed exposure to Delphinium and Aconitum spp, possibly resulting in sudden death.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0145-6296
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11824784-Aconitine,
pubmed-meshheading:11824784-Alkaloids,
pubmed-meshheading:11824784-Animals,
pubmed-meshheading:11824784-Cattle,
pubmed-meshheading:11824784-Cattle Diseases,
pubmed-meshheading:11824784-Disease Outbreaks,
pubmed-meshheading:11824784-Diterpenes,
pubmed-meshheading:11824784-Female,
pubmed-meshheading:11824784-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:11824784-Switzerland
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pubmed:year |
2002
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pubmed:articleTitle |
Diterpenoid alkaloid toxicosis in cattle in the Swiss Alps.
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pubmed:affiliation |
California Animal Health and Food Safety Laboratory System-Toxicology Laboratory, University of California, Davis 95616, USA.
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pubmed:publicationType |
Journal Article
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