rdf:type |
|
lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0016315,
umls-concept:C0023089,
umls-concept:C0040223,
umls-concept:C0060520,
umls-concept:C0124209,
umls-concept:C0242485,
umls-concept:C0449297,
umls-concept:C0543482,
umls-concept:C0681829,
umls-concept:C1522485,
umls-concept:C1708632,
umls-concept:C1879547,
umls-concept:C2348519,
umls-concept:C2745888
|
pubmed:issue |
1
|
pubmed:dateCreated |
2002-1-30
|
pubmed:abstractText |
Fourteen BALB/c mice were divided into two groups. One group served as the control and the second group was injected with a squamous cell carcinoma cell line to the tongue. After tumor development (1-4 weeks), mice were injected with a FITC conjugated CD3 marker to their tongues. Immediately after the marker injection, the clearance of the marker was measured using a laser spectroscopy system. The markers were excited by an argon laser at 488 nm and the fluorescence signal was measured as a function of time. A biopsy was taken from every mouse after the procedure and the excised tissue was histologically evaluated. Analysis of clearance times revealed a second order exponential decay for both groups with a slower pace of signal clearance for the sick mice.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1083-3668
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
14-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11818007-Animals,
pubmed-meshheading:11818007-Antibodies,
pubmed-meshheading:11818007-Antigens, CD3,
pubmed-meshheading:11818007-Biopsy,
pubmed-meshheading:11818007-Carcinoma, Squamous Cell,
pubmed-meshheading:11818007-Fluorescein-5-isothiocyanate,
pubmed-meshheading:11818007-Fluorescent Dyes,
pubmed-meshheading:11818007-Lasers,
pubmed-meshheading:11818007-Mice,
pubmed-meshheading:11818007-Mice, Inbred BALB C,
pubmed-meshheading:11818007-Neoplasm Transplantation,
pubmed-meshheading:11818007-Reference Values,
pubmed-meshheading:11818007-Tongue Neoplasms,
pubmed-meshheading:11818007-Tumor Cells, Cultured,
pubmed-meshheading:11818007-Tumor Markers, Biological
|
pubmed:year |
2002
|
pubmed:articleTitle |
Laser activated fluorescence measurements and morphological features: an in vivo study of clearance time of fluorescein isothiocyanate tagged cell markers.
|
pubmed:affiliation |
Tel-Aviv University, Department of Biomedical Engineering, Faculty of Engineering, Tel-Aviv 69978, Israel. gannot@eng.tau.ac.il
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|