Linked Life Data

11815436

Source:http://linkedlifedata.com/resource/pubmed/id/11815436

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2002-1-29
pubmed:abstractText
Recently, reactive oxygen species (ROS) have emerged as important molecules in cardiac hypertrophy. However, the ROS-dependent signal transduction mechanism remains to be elucidated. In this study, we examined the role of an ROS-sensitive transcriptional factor, NF-kappaB, and a mitogen-activated protein kinase kinase kinase, apoptosis signal-regulating kinase 1 (ASK1), in G-protein-coupled receptor (GPCR) agonist (angiotensin II, endothelin-1, phenylephrine)-induced cardiac hypertrophy in isolated rat neonatal cardiomyocytes.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1524-4539
pubmed:author
pubmed:issnType
Electronic
pubmed:day
29
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
509-15
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:11815436-Angiotensin II, pubmed-meshheading:11815436-Animals, pubmed-meshheading:11815436-Cardiomegaly, pubmed-meshheading:11815436-Cell Size, pubmed-meshheading:11815436-Cells, Cultured, pubmed-meshheading:11815436-Dose-Response Relationship, Drug, pubmed-meshheading:11815436-Endothelin-1, pubmed-meshheading:11815436-Heterotrimeric GTP-Binding Proteins, pubmed-meshheading:11815436-I-kappa B Proteins, pubmed-meshheading:11815436-Kinetics, pubmed-meshheading:11815436-MAP Kinase Kinase Kinase 5, pubmed-meshheading:11815436-MAP Kinase Kinase Kinases, pubmed-meshheading:11815436-Mutation, pubmed-meshheading:11815436-Myocardium, pubmed-meshheading:11815436-NF-kappa B, pubmed-meshheading:11815436-Phenylephrine, pubmed-meshheading:11815436-Rats, pubmed-meshheading:11815436-Rats, Wistar, pubmed-meshheading:11815436-Reactive Oxygen Species, pubmed-meshheading:11815436-Receptors, Cell Surface, pubmed-meshheading:11815436-Sarcomeres
pubmed:year
2002
pubmed:articleTitle
Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy.
pubmed:affiliation
Department of Pathophysiology, Osaka University Graduate School of Medicine, Osaka, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't