Source:http://linkedlifedata.com/resource/pubmed/id/11801755
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2002-1-21
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pubmed:abstractText |
Thymic carcinoma is a rare epithelial malignancy differentiated from thymoma by the presence of cytologically malignant cells. There are few reports of the treatment of locally advanced or metastatic thymic carcinoma. We describe a patient who sought treatment for thymic carcinoma metastatic to pleura, pericardium, retroperitoneum, and neck nodes. He was treated with neoadjuvant etoposide, ifosfamide, and cisplatin, and underwent resection. We then administered high-dose chemotherapy with autologous stem cell support, followed by radiation therapy. The patient remains in complete remission more than 4 years after diagnosis. To our knowledge, this is the first report of metastatic thymic carcinoma treated with neoadjuvant therapy and postoperative high-dose chemotherapy. Metastatic thymic carcinoma may be curable by aggressive combined therapies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0277-3732
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
566-9
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:11801755-Adult,
pubmed-meshheading:11801755-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:11801755-Carcinoma,
pubmed-meshheading:11801755-Combined Modality Therapy,
pubmed-meshheading:11801755-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:11801755-Humans,
pubmed-meshheading:11801755-Male,
pubmed-meshheading:11801755-Remission Induction,
pubmed-meshheading:11801755-Thoracic Neoplasms,
pubmed-meshheading:11801755-Thymus Neoplasms,
pubmed-meshheading:11801755-Transplantation, Autologous
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pubmed:year |
2001
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pubmed:articleTitle |
Multimodal treatment of metastatic thymic carcinoma including high-dose chemotherapy with autologous stem cell transplantation: report of a case with more than 4-year disease-free survival.
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pubmed:affiliation |
Department of Oncology, Soroka University Medical Center and the Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel.
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pubmed:publicationType |
Journal Article,
Case Reports
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