Source:http://linkedlifedata.com/resource/pubmed/id/11800146
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2002-1-21
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pubmed:abstractText |
We describe a unique patient with mosquito-bite hypersensitivity who had extremely high titres of Epstein-Barr virus antibodies. For many years he developed intractable ulcers on the sites of mosquito-bite. Epstein-Barr virus infection was detected in almost all inflammatory cells in the ulcers and in the peripheral blood lymphocytes by using in situ hybridization to Epstein-Barr virus-encoded small ribonucleic acids and by polymerase chain reaction to Epstein-Barr virus DNA. The inflammatory cells in the ulcers were positive for T-cell marker. Our results suggest that the Epstein-Barr virus infection in T cells may participate in the pathogenesis of exaggerated mosquito hypersensitivity and in delayed healing of ulcers on the sites of mosquito-bite.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0001-5555
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
360-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11800146-Adolescent,
pubmed-meshheading:11800146-Animals,
pubmed-meshheading:11800146-Culicidae,
pubmed-meshheading:11800146-DNA, Viral,
pubmed-meshheading:11800146-Epstein-Barr Virus Infections,
pubmed-meshheading:11800146-Herpesvirus 4, Human,
pubmed-meshheading:11800146-Humans,
pubmed-meshheading:11800146-In Situ Hybridization,
pubmed-meshheading:11800146-Insect Bites and Stings,
pubmed-meshheading:11800146-Leg Ulcer,
pubmed-meshheading:11800146-Male,
pubmed-meshheading:11800146-Severity of Illness Index,
pubmed-meshheading:11800146-T-Lymphocytes
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pubmed:articleTitle |
A case of exaggerated mosquito-bite hypersensitivity with Epstein-Barr virus-positive inflammatory cells in the bite lesion.
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pubmed:affiliation |
Department of Dermatology, Faculty of Medicine, Tottori University, Yonago, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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