Source:http://linkedlifedata.com/resource/pubmed/id/11797170
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2002-1-17
|
| pubmed:abstractText |
Few large prospective studies of adverse reactions after bacille Calmette-Guérin (BCG) vaccination are available. In a prospective national study of such adverse reactions among 918 subjects (aged 1 day to 54 years) over a 14-month period, 45 vaccinees (5%) reported 53 adverse reactions (23 injection-site abscesses, 14 severe local reactions, 10 cases of lymphadenitis, and 6 other reactions). Only 1% of vaccinees required medical attention. Reactions, particularly lymphadenitis, were significantly less common in infants <6 months old (but not in subjects aged > or =6 months) vaccinated by trained (vs. untrained) providers (relative risk [RR], 0.24; 95% confidence interval [CI], 0.09-0.68). Injection-site abscesses (RR, 2.96; 95% CI, 1.11-7.90) and severe local reactions (RR, 4.93; 95% CI, 1.11-21.90) were significantly more common in older vaccinees. Local reactions were more frequently reported by adult females than by adult males (RR, 7.18; 95% CI, 1.59-32.45). Adverse reactions were not significantly associated with any currently available vaccine batch, previous receipt of BCG vaccine, or concomitant administration of other vaccines.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
1537-6591
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| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:day |
15
|
| pubmed:volume |
34
|
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
447-53
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:11797170-Adolescent,
pubmed-meshheading:11797170-Adult,
pubmed-meshheading:11797170-BCG Vaccine,
pubmed-meshheading:11797170-Child,
pubmed-meshheading:11797170-Child, Preschool,
pubmed-meshheading:11797170-Female,
pubmed-meshheading:11797170-Humans,
pubmed-meshheading:11797170-Infant,
pubmed-meshheading:11797170-Infant, Newborn,
pubmed-meshheading:11797170-Male,
pubmed-meshheading:11797170-Middle Aged,
pubmed-meshheading:11797170-Prospective Studies
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
National study of adverse reactions after vaccination with bacille Calmette-Guérin.
|
| pubmed:affiliation |
National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Royal Alexandra Hospital for Children and the University of Sydney, Sydney, Australia.
|
| pubmed:publicationType |
Journal Article
|