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pubmed:abstractText |
In chronic obstructive pulmonary disease (COPD) patients with acute respiratory failure (ARF), bronchodilating agents administered by inhalation have, in general, little effect on dynamic hyperinflation and concurrent static intrinsic positive end-expiratory pressure (PEEPi,st). Since in COPD the severely obstructed segments of the lung may not be reached by inhaled medication, we reasoned that drug efficiency may be enhanced by intravenous administration of the agent.
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pubmed:affiliation |
Department of Surgical, S. Anna Hospital, University of Ferrara, Ferrara, Corso Giovecca 203, 44100 Ferrara, Italy. vlc@dns.unife.it
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