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pubmed-article:11796642pubmed:abstractTextThe sequence of the Mycobacterium leprae homologue of ESAT-6 shows only 36% amino acid correspondence to that from Mycobacterium tuberculosis. Anti-M. leprae ESAT-6 polyclonal and monoclonal antibodies and T-cell hybridomas reacted only with the homologous protein and allowed identification of the B- and T-cell epitopes. The protein is expressed in M. leprae and appears in the cell wall fraction. Thus, M. leprae ESAT-6 shows promise as a specific diagnostic agent for leprosy.lld:pubmed
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pubmed-article:11796642pubmed:articleTitleAntigenic specificity of the Mycobacterium leprae homologue of ESAT-6.lld:pubmed
pubmed-article:11796642pubmed:affiliationDepartment of Microbiology, Colorado State University, Fort Collins, Colorado 80523-1677, USA. john.spencer@colostate.edulld:pubmed
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