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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-1-17
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pubmed:abstractText |
The sequence of the Mycobacterium leprae homologue of ESAT-6 shows only 36% amino acid correspondence to that from Mycobacterium tuberculosis. Anti-M. leprae ESAT-6 polyclonal and monoclonal antibodies and T-cell hybridomas reacted only with the homologous protein and allowed identification of the B- and T-cell epitopes. The protein is expressed in M. leprae and appears in the cell wall fraction. Thus, M. leprae ESAT-6 shows promise as a specific diagnostic agent for leprosy.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-10024600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-10694977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-10823800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-10992494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-11234002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-11378400,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-11565110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-1678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-1730920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-2201679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-2454713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-2778316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-310843,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-3126253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-6166712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-7108955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-714156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-7729876,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-8446027,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-8557334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-8631702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-8871652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-8926118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-9596726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-9634230,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-9787646,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11796642-9846755
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1010-3
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:11796642-Amino Acid Sequence,
pubmed-meshheading:11796642-Animals,
pubmed-meshheading:11796642-Antibody Specificity,
pubmed-meshheading:11796642-Antigens, Bacterial,
pubmed-meshheading:11796642-Bacterial Proteins,
pubmed-meshheading:11796642-Cloning, Molecular,
pubmed-meshheading:11796642-Epitopes, B-Lymphocyte,
pubmed-meshheading:11796642-Epitopes, T-Lymphocyte,
pubmed-meshheading:11796642-Leprosy,
pubmed-meshheading:11796642-Mice,
pubmed-meshheading:11796642-Mice, Inbred BALB C,
pubmed-meshheading:11796642-Molecular Sequence Data,
pubmed-meshheading:11796642-Mycobacterium leprae,
pubmed-meshheading:11796642-Mycobacterium tuberculosis,
pubmed-meshheading:11796642-Recombinant Fusion Proteins,
pubmed-meshheading:11796642-Sequence Analysis, Protein,
pubmed-meshheading:11796642-Sequence Homology, Amino Acid,
pubmed-meshheading:11796642-Subcellular Fractions
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pubmed:year |
2002
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pubmed:articleTitle |
Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6.
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pubmed:affiliation |
Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523-1677, USA. john.spencer@colostate.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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