rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
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pubmed:dateCreated |
2002-1-15
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pubmed:abstractText |
Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells. They bind and internalise micro-organisms and their products including Gram-positive bacteria (lipoteichoic acid), Gram-negative bacteria (lipopolysaccharide), intracellular bacteria and CpG DNA. SR can alter cell morphology and their expression is affected by various cytokines. SR are involved in lipid metabolism and bind modified low-density lipoproteins.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Lipoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Scavenger,
http://linkedlifedata.com/resource/pubmed/chemical/Scarb1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class B
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
0952-7915
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
14
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
123-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11790542-Animals,
pubmed-meshheading:11790542-Dendritic Cells,
pubmed-meshheading:11790542-Humans,
pubmed-meshheading:11790542-Immunity, Innate,
pubmed-meshheading:11790542-Macrophages,
pubmed-meshheading:11790542-Membrane Proteins,
pubmed-meshheading:11790542-Receptors, Immunologic,
pubmed-meshheading:11790542-Receptors, Lipoprotein,
pubmed-meshheading:11790542-Receptors, Scavenger,
pubmed-meshheading:11790542-Scavenger Receptors, Class B
|
pubmed:year |
2002
|
pubmed:articleTitle |
Scavenger receptors in innate immunity.
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pubmed:affiliation |
Sir William Dunn School of Pathology, University of Oxford, South Parks Road, ox1 3RE, Oxford, UK.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|