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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2002-1-15
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pubmed:abstractText |
Affymetrix oligonucleotide arrays simultaneously measure the abundances of thousands of mRNAs in biological samples. Comparability of array results is necessary for the creation of large-scale gene expression databases. The standard strategy for normalizing oligonucleotide array readouts has practical drawbacks. We describe alternative normalization procedures for oligonucleotide arrays based on a common pool of known biotin-labeled cRNAs spiked into each hybridization.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-10359783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-10367887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-10464095,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-10773095,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-10964511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-11052945,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-11074587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-11101804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-11134512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-11222780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-9415887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-9634850,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-9702192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-9845373,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11790258-9851916
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-6914
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
RESEARCH0055
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:11790258-Animals,
pubmed-meshheading:11790258-Biotinylation,
pubmed-meshheading:11790258-Caenorhabditis elegans Proteins,
pubmed-meshheading:11790258-Gene Expression Profiling,
pubmed-meshheading:11790258-Kinetics,
pubmed-meshheading:11790258-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:11790258-RNA, Complementary,
pubmed-meshheading:11790258-RNA, Messenger,
pubmed-meshheading:11790258-Reproducibility of Results,
pubmed-meshheading:11790258-Sensitivity and Specificity
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pubmed:year |
2001
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pubmed:articleTitle |
Evaluation of normalization procedures for oligonucleotide array data based on spiked cRNA controls.
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pubmed:affiliation |
Department of Genomics, Genetics Institute/Wyeth-Ayerst Research, Cambridge, MA 02140, USA. ahill@genetics.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies
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