Source:http://linkedlifedata.com/resource/pubmed/id/11781501
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
2002-1-8
|
pubmed:abstractText |
In previous studies, genetic correlations were observed between hypnotic sensitivity to ethanol and high-affinity neurotensin receptor (NTS1) binding. Provisional quantitative trait loci (QTLs) were identified for these traits, and some of these QTLs were found on common chromosomal regions. In continued efforts to examine the relationship between NTS1 binding capacity and hypnotic sensitivity to ethanol, studies were designed to confirm correlations between NTS1 densities in the brain, duration of ethanol-induced loss of righting reflex (LORR), and blood ethanol concentrations at regain of righting reflex (BECRR). Another purpose of the study was to confirm QTLs for these traits.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0145-6008
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1699-707
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:11781501-Animals,
pubmed-meshheading:11781501-Chromosome Mapping,
pubmed-meshheading:11781501-Corpus Striatum,
pubmed-meshheading:11781501-Ethanol,
pubmed-meshheading:11781501-Female,
pubmed-meshheading:11781501-Hypnotics and Sedatives,
pubmed-meshheading:11781501-Male,
pubmed-meshheading:11781501-Mice,
pubmed-meshheading:11781501-Mice, Inbred Strains,
pubmed-meshheading:11781501-Phenotype,
pubmed-meshheading:11781501-Postural Balance,
pubmed-meshheading:11781501-Quantitative Trait, Heritable,
pubmed-meshheading:11781501-Rats,
pubmed-meshheading:11781501-Rats, Inbred Strains,
pubmed-meshheading:11781501-Receptors, Neurotensin,
pubmed-meshheading:11781501-Reflex
|
pubmed:year |
2001
|
pubmed:articleTitle |
Confirmation of correlations and common quantitative trait loci between neurotensin receptor density and hypnotic sensitivity to ethanol.
|
pubmed:affiliation |
University of Colorado Health Sciences Center, Department of Pharmaceutical Sciences, Denver, Colorado 80262, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|