Linked Life Data

11778741

Source:http://linkedlifedata.com/resource/pubmed/id/11778741

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-1-7
pubmed:abstractText
According to the view of differentiation-related alterations in the glycosylation pattern of neurones, recent studies have shown development dependent expression patterns of lactoseries carbohydrate epitopes, CD15 and HNK-1, on olfactory receptor neurones in rats and chicks. In order to evaluate a general role for these epitopes during development of vertebrate olfactory receptor neurones, this investigation focuses on the situation in the mouse, bovine and Xenopus olfactory epithelium. In all three species CD15 expression was found on a subpopulation of morphologically mature receptor cells starting at the time of initial synaptogenesis. Whereas for bovine and Xenopus the timetable of HNK-1 expression is similar to that described for the chick, suggesting involvement in pathfinding, in the mouse HNK-1 is found on immature cells when mature CD15 positive receptor cells could already be discerned. By our results a role for CD15 during establishment of synaptic contacts and for HNK-1 during their formation is suggested.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0924-3860
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-71
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Differential expression of two carbohydrate epitopes, CD15 and HNK-1, in developing vertebrate olfactory receptor neurones.
pubmed:affiliation
Institut I für Anatomie der University zu Köln, Germany. stefan.arnhold@uni-koeln.de
pubmed:publicationType
Journal Article