Linked Life Data

11770114

Source:http://linkedlifedata.com/resource/pubmed/id/11770114

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2001-12-24
pubmed:abstractText
The diagnosis of visceral leishmaniasis is difficult. Due to the limitations of direct methods to detect parasites, indirect immunological methods are widely employed. The simple affordable and sensitive/specific direct agglutination test (DAT) is perhaps the most important diagnostic tool under field conditions. A significant improvement of this test is the use of a freeze-dried antigen, which is heat-stable and has a long shelf-live even under harsh conditions. The performance of this antigen in DAT has been evaluated using samples collected in East Africa. The results of these studies are presented. The detection of Leishmania infection in HIV-co-infected patients is difficult. The combination of DAT-PCR may be useful for the detection of parasite infection in these patients. Finally, we present data to show that the DAT based on the freeze-dried antigen can also be used for the detection of anti-Leishmania antibodies in dogs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0300-8584
pubmed:author
pubmed:issnType
Print
pubmed:volume
190
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-71
pubmed:dateRevised
2007-2-21
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Development and application of 'simple' diagnostic tools for visceral leishmaniasis.
pubmed:affiliation
Koninklijk Instituut voor de Tropen, Royal Tropical Institute (KIT) Biomedical Research, Amsterdam, The Netherlands. H.Schallig@kit.nl
pubmed:publicationType
Journal Article, Comparative Study