Source:http://linkedlifedata.com/resource/pubmed/id/11763392
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2001-12-12
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pubmed:abstractText |
Fatal calciphylaxis (CPX) occurred in two 71-year-old females both requiring haemodialysis for end-stage renal disease. Case 2 also had an associated follicular lymphoplasmocytoid lymphoma. Although laboratory tests disclosed normal coagulation parameters, this woman had a striking cutaneous histological picture of vessel thrombosis and finally died of disseminated intravascular coagulation. CPX is a rare but potentially life-threatening complication of renal failure. The clinical picture is primarily characterized by livedoid purpura with subsequent cutaneous ischaemia and painful ulcerations. Cutaneous ischaemic phenomena are sustained by a progressive process of vascular calcification and thrombosis involving small to medium size arteries of the dermis and subcutis. Although not yet clearly explained, the pathogenetic role of a predisposing hypercoagulability state is currently the most frequently considered hypothesis.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0926-9959
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
461-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11763392-Aged,
pubmed-meshheading:11763392-Biopsy, Needle,
pubmed-meshheading:11763392-Calciphylaxis,
pubmed-meshheading:11763392-Disease Progression,
pubmed-meshheading:11763392-Fatal Outcome,
pubmed-meshheading:11763392-Female,
pubmed-meshheading:11763392-Humans,
pubmed-meshheading:11763392-Kidney Failure, Chronic,
pubmed-meshheading:11763392-Long-Term Care,
pubmed-meshheading:11763392-Renal Dialysis,
pubmed-meshheading:11763392-Severity of Illness Index
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pubmed:year |
2001
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pubmed:articleTitle |
Calciphylaxis in two patients with end-stage renal disease.
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pubmed:affiliation |
Department of Dermatology, A. Murri Hospital Via dei Colli, AN, Italy. dermjesi@yahoo.it
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pubmed:publicationType |
Journal Article,
Case Reports
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