Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1975-12-20
|
| pubmed:abstractText |
The effects of lidoplazine on K-metabolism were investigated in two types of experiments. (1) K and Na concentrations were measured in plasma, heart, diaphragm and erythrocytes in normo- and hypokalaemic rats with or without chronic (1 month) lidoplazine treatment. Total body weight, heart weight, dry weight/wet weight ratios and extracellular space were also determined. (2) Radioactive K influx in the heart was measured in acute in vitro experiments with or without lidoplazine. It is demonstrated that while lidoflazine has no effect on the Na and K distribution of normokalaemic animals, it has rather a K-saving effect in conditions of severe loss of intra- and extracellular K-ions. In normal in vitro preparations the unidirectional K-influx is not affected by lidoflazine.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0014-2999
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
33
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
81-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:1175693-Animals,
pubmed-meshheading:1175693-Body Water,
pubmed-meshheading:1175693-Body Weight,
pubmed-meshheading:1175693-Diaphragm,
pubmed-meshheading:1175693-Erythrocytes,
pubmed-meshheading:1175693-Extracellular Space,
pubmed-meshheading:1175693-Heart,
pubmed-meshheading:1175693-Heart Atria,
pubmed-meshheading:1175693-Heart Ventricles,
pubmed-meshheading:1175693-Hypokalemia,
pubmed-meshheading:1175693-Lidoflazine,
pubmed-meshheading:1175693-Male,
pubmed-meshheading:1175693-Organ Size,
pubmed-meshheading:1175693-Piperazines,
pubmed-meshheading:1175693-Potassium,
pubmed-meshheading:1175693-Potassium Deficiency,
pubmed-meshheading:1175693-Rats,
pubmed-meshheading:1175693-Sodium
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
Lidoplazine and Na and K distribution in normo-and hypokalaemic rats.
|
| pubmed:publicationType |
Journal Article
|