Source:http://linkedlifedata.com/resource/pubmed/id/11754857
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2001-12-28
|
| pubmed:abstractText |
After severe sepsis, there is an increase of Th2 cytokine and a decrease in Th1 cytokine that may account for impaired cellular immunity. The aim of this study is to evaluate the Th1, Th2 cytokine balance in the serum, peritoneal lavage fluid (PLF) and liver mononuclear cells (MNC) of experimental peritonitis mice, and determine the effect of interleukin-12 (IL-12), a cytokine stimulating Th1 cytokine production, when administered to septic mice.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0002-9610
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
182
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
491-7
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| pubmed:dateRevised |
2008-11-21
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| pubmed:meshHeading |
pubmed-meshheading:11754857-Animals,
pubmed-meshheading:11754857-Interferon-gamma,
pubmed-meshheading:11754857-Interleukin-12,
pubmed-meshheading:11754857-Leukocytes, Mononuclear,
pubmed-meshheading:11754857-Liver,
pubmed-meshheading:11754857-Male,
pubmed-meshheading:11754857-Mice,
pubmed-meshheading:11754857-Mice, Inbred BALB C,
pubmed-meshheading:11754857-Peritoneal Lavage,
pubmed-meshheading:11754857-Peritonitis,
pubmed-meshheading:11754857-Recombinant Proteins,
pubmed-meshheading:11754857-Sepsis
|
| pubmed:year |
2001
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| pubmed:articleTitle |
Severe sepsis induces deficient interferon-gamma and interleukin-12 production, but interleukin-12 therapy improves survival in peritonitis.
|
| pubmed:affiliation |
First Department of Surgery, National Defense Medical College, Namiki 3-2, 359-8513, Tokorozawa, Saitama, Japan. satoshi@me.ndmc.ac.jp
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| pubmed:publicationType |
Journal Article
|