Source:http://linkedlifedata.com/resource/pubmed/id/11754610
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2001-12-28
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pubmed:abstractText |
Eleven sesquiterpenes (1-11) and one long chain aldehyde (12) have been isolated from the dichloromethane extract of the red alga Laurencia scoparia. Four of them are new natural products. Scopariol (1) is a new natural product with an unusual rearranged chamigrane-type structure. The other three are beta-chamigrenes: isorigidol (2), (+)-3-(Z)-bromomethylidene-10 beta-bromo-beta-chamigrene (3), and (-)-3-(E)-bromomethylidene-10 beta-bromo-beta-chamigrene (4). The in vitro activity of compounds 1-12 against the parasitant stage of Nippostrongylus brasiliensis (L4) has been studied.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1552-5
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11754610-Animals,
pubmed-meshheading:11754610-Anthelmintics,
pubmed-meshheading:11754610-Brazil,
pubmed-meshheading:11754610-Chromatography, Thin Layer,
pubmed-meshheading:11754610-Molecular Conformation,
pubmed-meshheading:11754610-Molecular Structure,
pubmed-meshheading:11754610-Nippostrongylus,
pubmed-meshheading:11754610-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:11754610-Rhodophyta,
pubmed-meshheading:11754610-Sesquiterpenes,
pubmed-meshheading:11754610-Spectroscopy, Fourier Transform Infrared,
pubmed-meshheading:11754610-Spiro Compounds,
pubmed-meshheading:11754610-Stereoisomerism,
pubmed-meshheading:11754610-Structure-Activity Relationship
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pubmed:year |
2001
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pubmed:articleTitle |
New sesquiterpene derivatives from the red alga Laurencia scoparia. Isolation, structure determination, and anthelmintic activity.
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pubmed:affiliation |
Cátedra de Química Farmacéutica, Facultad de Química, Universidad de la República, Avenida Gral. Flores 2124, Montevideo, Uruguay.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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