Linked Life Data

11754238

Source:http://linkedlifedata.com/resource/pubmed/id/11754238

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-12-25
pubmed:abstractText
During the course of researching the embryologic etiology of conjoined twins, more than 1260 individual cases were collected from the literature and the reported abnormal anatomy tabulated and evaluated in the light of known embryology. It soon became apparent that the association of conjoined twins and their parasites with fetuses in fetu, acardiacs, and teratomas was more frequent than could be attributed to chance. These anomalous fetuses form a continuum, strongly suggesting that they are all variations of abnormal conjoined twinning, with the site of union and the extent of damage (or defect) of one embryo resulting in (1) an externally attached parasitic twin, (2) an enclosed fetus in fetu, (3) an internal teratoma, or (4) an acardiac connected via the placenta. Common patterns among them are a family history of twinning, the predominance of females, and the frequent presence of a twin or triplet accompanying the malformation. The several reports of chromosomal abnormality suggest that perhaps, at least on occasion, it is a genetically imperfect embryo that develops into a defective fetus. Of singular importance is the fact that rarely, if ever, is either a functional heart or a competent brain found in any of these abnormal fetuses, suggesting that the etiology of all of them is a primary cardiac malformation with secondary disruption in the development of the brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0897-3806
pubmed:author
pubmed:copyrightInfo
Copyright 2001 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
428-44
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Parasitic conjoined twins: external, internal (fetuses in fetu and teratomas), and detached (acardiacs).
pubmed:publicationType
Journal Article, Review