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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-12-25
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pubmed:abstractText |
Although no therapeutic regimen has received Food and Drug Administration approval for treating children with chronic hepatitis C viral infection (CHC), there have been a number of pediatric interferon-alpha (IFN-alpha) trials. The purpose of this study was to perform a critical review of these trials to determine 1) end-of-treatment (ETR) and sustained-response (SR) rates, 2) predictors of response to therapy, and 3) safety of and tolerance to IFN-alpha in children with CHC.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0277-2116
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
52-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11753165-Adolescent,
pubmed-meshheading:11753165-Adult,
pubmed-meshheading:11753165-Antiviral Agents,
pubmed-meshheading:11753165-Child,
pubmed-meshheading:11753165-Child, Preschool,
pubmed-meshheading:11753165-Female,
pubmed-meshheading:11753165-Genotype,
pubmed-meshheading:11753165-Hepacivirus,
pubmed-meshheading:11753165-Hepatitis C, Chronic,
pubmed-meshheading:11753165-Humans,
pubmed-meshheading:11753165-Interferon-alpha,
pubmed-meshheading:11753165-MEDLINE,
pubmed-meshheading:11753165-Male,
pubmed-meshheading:11753165-Polymerase Chain Reaction,
pubmed-meshheading:11753165-RNA, Viral,
pubmed-meshheading:11753165-Recurrence,
pubmed-meshheading:11753165-Safety,
pubmed-meshheading:11753165-Treatment Outcome
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pubmed:year |
2002
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pubmed:articleTitle |
An analysis of published trials of interferon monotherapy in children with chronic hepatitis C.
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pubmed:affiliation |
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Meta-Analysis
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