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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2001-12-25
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pubmed:abstractText |
Histological studies have shown that the two sialoproteins, bone sialoprotein (BSP) and osteopontin (OPN), are induced in multiple types of cancer. We have recently found that these proteins are bound in serum to complement factor H and that the complex must be disrupted to generate free protein to measure their total levels. We hypothesized that measuring total BSP and OPN levels would provide informative markers for the detection of cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4060-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11751502-Breast Neoplasms,
pubmed-meshheading:11751502-Colonic Neoplasms,
pubmed-meshheading:11751502-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:11751502-Female,
pubmed-meshheading:11751502-Humans,
pubmed-meshheading:11751502-Integrin-Binding Sialoprotein,
pubmed-meshheading:11751502-Lung Neoplasms,
pubmed-meshheading:11751502-Male,
pubmed-meshheading:11751502-Osteopontin,
pubmed-meshheading:11751502-ROC Curve,
pubmed-meshheading:11751502-Reference Values,
pubmed-meshheading:11751502-Sensitivity and Specificity,
pubmed-meshheading:11751502-Sialoglycoproteins,
pubmed-meshheading:11751502-Tumor Markers, Biological
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pubmed:year |
2001
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pubmed:articleTitle |
Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer.
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pubmed:affiliation |
Division of Geriatrics, Department of Medicine, The Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA. ndarko@jhmi.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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