Source:http://linkedlifedata.com/resource/pubmed/id/11751232
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2001-12-25
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pubmed:abstractText |
MELTING computes the enthalpy and entropy of an oligonucleotide duplex helix-coil transition, and then its melting temperature. The program uses the method of nearest-neighbours. The set of thermodynamic parameters can be easily customized. The program provides several correction methods for the concentration of salt. MELTING is a free program, available at no cost and open-source. Perl scripts are provided to show how MELTING can be used to construct more ambitious programs. AVAILABILITY: MELTING is available for several platforms (http://www.pasteur.fr/recherche/unites/neubiomol/meltinghome.html) and is accessible via a www server (http://bioweb.pasteur.fr/seqanal/interfaces/melting.html). CONTACT: nl223@cus.cam.ac.uk
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1367-4803
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1226-7
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pubmed:meshHeading | |
pubmed:year |
2001
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pubmed:articleTitle |
MELTING, computing the melting temperature of nucleic acid duplex.
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pubmed:affiliation |
Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK. nl223@cus.cam.ac.uk
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pubmed:publicationType |
Journal Article
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