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rdf:type |
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lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0022180,
umls-concept:C0027747,
umls-concept:C0030685,
umls-concept:C0033487,
umls-concept:C0037473,
umls-concept:C0205391,
umls-concept:C0205409,
umls-concept:C0220839,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1963578
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pubmed:issue |
6
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pubmed:dateCreated |
2001-12-18
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pubmed:abstractText |
Controversy persists concerning the mechanisms and role of general anesthetic inhibition of glutamate release from nerve endings. To determine the generality of this effect and to control for methodologic differences between previous studies, the authors analyzed the presynaptic effects of isoflurane and propofol on glutamate release from nerve terminals isolated from several species and brain regions.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Inhalation,
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Intravenous,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Isoflurane,
http://linkedlifedata.com/resource/pubmed/chemical/Propofol,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, GABA-A,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Channel Blockers,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Channels
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0003-3022
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1460-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11748406-Anesthetics, Inhalation,
pubmed-meshheading:11748406-Anesthetics, Intravenous,
pubmed-meshheading:11748406-Animals,
pubmed-meshheading:11748406-Cerebral Cortex,
pubmed-meshheading:11748406-Glutamic Acid,
pubmed-meshheading:11748406-Guinea Pigs,
pubmed-meshheading:11748406-Hippocampus,
pubmed-meshheading:11748406-Isoflurane,
pubmed-meshheading:11748406-Mice,
pubmed-meshheading:11748406-Neostriatum,
pubmed-meshheading:11748406-Nerve Endings,
pubmed-meshheading:11748406-Propofol,
pubmed-meshheading:11748406-Rats,
pubmed-meshheading:11748406-Receptors, GABA-A,
pubmed-meshheading:11748406-Sodium Channel Blockers,
pubmed-meshheading:11748406-Sodium Channels,
pubmed-meshheading:11748406-Species Specificity,
pubmed-meshheading:11748406-Synaptosomes
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pubmed:year |
2001
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pubmed:articleTitle |
Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol.
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pubmed:affiliation |
Department of Anesthesiology, Weill Medical College of Cornell University, New York, New York 10021, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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