Source:http://linkedlifedata.com/resource/pubmed/id/11747166
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
2001-12-17
|
pubmed:abstractText |
We tested whether fractional flow reserve (FFR) discriminates between suboptimally and optimally deployed stents. Latex tubes (diameter solidus in circle = 4 mm) with diameter stenosis 40% (n = 3), 50% (n = 3) and 60% (n = 3) were tested in a pulsatile flow system, using water. Measurements were done at baseline (n = 9; FFR/QCA) and after suboptimal (SOD; 3-mm balloon at 8 atm) and optimal (OD; 4 mm balloon at 16 atm) deployment of a 35-mm stent (n = 6; FFR/QCA/IVUS). Varying Q from 150 to 50 ml/min increased FFR by 2-7%. Conversely, at 100 ml/min, FFR increased by only 0.8% from SOD to OD (P < 0.05). Extrapolating data to blood flow, the gain in FFR from SOD to OD is less than 5% for Q = 100 ml/min, while FFR may increase by 15-20% by changes in blood flow from 50 to 150 ml/min. We conclude that IVUS and QCA are more appropriate for the assessment of optimal stent deployment.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1522-1946
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright 2001 Wiley-Liss, Inc.
|
pubmed:issnType |
Print
|
pubmed:volume |
54
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
363-75
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11747166-Blood Flow Velocity,
pubmed-meshheading:11747166-Coronary Angiography,
pubmed-meshheading:11747166-Coronary Circulation,
pubmed-meshheading:11747166-Coronary Stenosis,
pubmed-meshheading:11747166-Coronary Vessels,
pubmed-meshheading:11747166-Equipment Design,
pubmed-meshheading:11747166-Humans,
pubmed-meshheading:11747166-Severity of Illness Index,
pubmed-meshheading:11747166-Stents,
pubmed-meshheading:11747166-Treatment Outcome,
pubmed-meshheading:11747166-Ultrasonography, Interventional
|
pubmed:year |
2001
|
pubmed:articleTitle |
In vitro study of FFR, QCA, and IVUS for the assessment of optimal stent deployment.
|
pubmed:affiliation |
Institute Biomedical Technology IBITECH, Hydraulics Laboratory, Ghent University, Belgium. koen.matthys@rug.ac.be
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|