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pubmed-article:11745288pubmed:abstractTextTwo-thirds of patients with squamous cell carcinomas of the head and neck (SCCHN) at diagnosis have advanced disease with projected 5-year survival rates of 30%. In those patients with distant metastatic or previously treated recurrent disease, response rate to the standard regimen of cisplatin and 5-fluorouracil is approximately 30%. The authors investigated the use of paclitaxel and carboplatin in a limited Phase II study in recurrent or metastatic SCCHN to evaluate tumor response, time to progression, survival, and toxicities of this regimen.lld:pubmed
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pubmed-article:11745288pubmed:copyrightInfoCopyright 2001 American Cancer Society.lld:pubmed
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pubmed-article:11745288pubmed:dateRevised2006-4-24lld:pubmed
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pubmed-article:11745288pubmed:articleTitlePhase II evaluation of paclitaxel in combination with carboplatin in advanced head and neck carcinoma.lld:pubmed
pubmed-article:11745288pubmed:affiliationDepartment of Medicine, Division of Hematology/Oncology, Loyola University Medical Center/Cardinal Bernardin Cancer Center, 2160 South First Avenue, Maywood, IL 60153, USA. jclark@lumc.edulld:pubmed
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