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rdf:type |
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lifeskim:mentions |
umls-concept:C0030705,
umls-concept:C0078058,
umls-concept:C0220901,
umls-concept:C0302350,
umls-concept:C0302600,
umls-concept:C0476089,
umls-concept:C0597357,
umls-concept:C1171892,
umls-concept:C1334306,
umls-concept:C1704259,
umls-concept:C1705987
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pubmed:issue |
10
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pubmed:dateCreated |
2001-12-17
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pubmed:abstractText |
Vascular endothelial growth factor (VEGF) is an important endothelial cell mitogen associated with increased angiogenesis and aggressive tumor behavior. Its stimulating effect on endothelial cells basically is dependent on the presence of specific VEGF receptors, such as the flk-1(KDR) receptor. This study investigates the roles of VEGF and of a functionally intact angiogenic pathway, "VEGF/flk-1(KDR)," in patients with endometrial carcinoma and their significance in prognosis and therapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Endothelial Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Lymphokines,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Vascular Endothelial...,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2001 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2569-77
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11745191-Adult,
pubmed-meshheading:11745191-Aged,
pubmed-meshheading:11745191-Aged, 80 and over,
pubmed-meshheading:11745191-Disease Progression,
pubmed-meshheading:11745191-Endometrial Neoplasms,
pubmed-meshheading:11745191-Endothelial Growth Factors,
pubmed-meshheading:11745191-Female,
pubmed-meshheading:11745191-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11745191-Humans,
pubmed-meshheading:11745191-Lymphokines,
pubmed-meshheading:11745191-Microcirculation,
pubmed-meshheading:11745191-Middle Aged,
pubmed-meshheading:11745191-Neovascularization, Pathologic,
pubmed-meshheading:11745191-Prognosis,
pubmed-meshheading:11745191-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:11745191-Receptors, Growth Factor,
pubmed-meshheading:11745191-Receptors, Vascular Endothelial Growth Factor,
pubmed-meshheading:11745191-Risk Assessment,
pubmed-meshheading:11745191-Survival Analysis,
pubmed-meshheading:11745191-Tumor Markers, Biological,
pubmed-meshheading:11745191-Vascular Endothelial Growth Factor A,
pubmed-meshheading:11745191-Vascular Endothelial Growth Factors
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pubmed:year |
2001
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pubmed:articleTitle |
The angiogenic "vascular endothelial growth factor/flk-1(KDR) receptor" pathway in patients with endometrial carcinoma: prognostic and therapeutic implications.
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pubmed:affiliation |
Department of Pathology, Democritus University of Thrace, Alexandroupolis, Greece. targ@her.forthnet.gr
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pubmed:publicationType |
Journal Article
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