rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2001-12-17
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pubmed:abstractText |
To examine how hepatocyte growth factor (HGF) affects cell-cell adhesion junctions on scattering in prostate cancer cells. HGF is known to induce scattering (dispersion of clustered cells into single cells) in various epithelial cells, including prostate cancer cells, but the mechanisms surrounding this action are not fully understood. Cell-cell adhesion junctions are composed of E-cadherin and its associated intracellular catenins and play important roles in the maintenance of cell integrity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CTNNA1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CTNNB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cadherins,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatocyte Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/alpha Catenin,
http://linkedlifedata.com/resource/pubmed/chemical/beta Catenin
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1527-9995
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1064-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11744496-Cadherins,
pubmed-meshheading:11744496-Cell Communication,
pubmed-meshheading:11744496-Cytoskeletal Proteins,
pubmed-meshheading:11744496-Hepatocyte Growth Factor,
pubmed-meshheading:11744496-Humans,
pubmed-meshheading:11744496-Male,
pubmed-meshheading:11744496-Neoplasm Proteins,
pubmed-meshheading:11744496-Prostatic Neoplasms,
pubmed-meshheading:11744496-Trans-Activators,
pubmed-meshheading:11744496-Tumor Cells, Cultured,
pubmed-meshheading:11744496-alpha Catenin,
pubmed-meshheading:11744496-beta Catenin
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pubmed:year |
2001
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pubmed:articleTitle |
Effects of hepatocyte growth factor on E-cadherin-mediated cell-cell adhesion in DU145 prostate cancer cells.
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pubmed:affiliation |
Department of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine, Suita, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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