rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2001-12-14
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pubmed:abstractText |
Hydroxyurea improves hematologic values and decreases vaso-occlusive complications in adults and children with sickle cell anemia (SCA), but has not been tested in infants before the onset of chronic organ dysfunction. We conducted a collaborative pilot trial of hydroxyurea in infants with SCA to assess its (1) feasibility of administration, (2) toxicity, (3) hematologic effects, and (4) effect on spleen function.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0022-3476
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
790-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11743503-Age Factors,
pubmed-meshheading:11743503-Anemia, Sickle Cell,
pubmed-meshheading:11743503-Antisickling Agents,
pubmed-meshheading:11743503-Blood Cell Count,
pubmed-meshheading:11743503-Child, Preschool,
pubmed-meshheading:11743503-Feasibility Studies,
pubmed-meshheading:11743503-Female,
pubmed-meshheading:11743503-Hematologic Diseases,
pubmed-meshheading:11743503-Hemoglobins,
pubmed-meshheading:11743503-Humans,
pubmed-meshheading:11743503-Hydroxyurea,
pubmed-meshheading:11743503-Infant,
pubmed-meshheading:11743503-Male,
pubmed-meshheading:11743503-Pilot Projects,
pubmed-meshheading:11743503-Splenic Diseases,
pubmed-meshheading:11743503-Time Factors
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pubmed:year |
2001
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pubmed:articleTitle |
A two-year pilot trial of hydroxyurea in very young children with sickle-cell anemia.
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pubmed:affiliation |
Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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