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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-12-19
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pubmed:abstractText |
VirB2 propilin is processed by the removal of a 47-amino-acid signal peptide to generate a 74-amino-acid peptide product in both Escherichia coli and Agrobacterium tumefaciens. The cleaved VirB2 protein is further cyclized to form the T pilin in A. tumefaciens but not in E. coli. Mutations in the signal peptidase cleavage sequence of VirB2 propilin cause the formation of aberrant T pilin and also severely attenuate virulence. No T pilus was observed in these mutants. The potential role of the exact VirB2 propilin cleavage and cyclization in T pilus biogenesis and virulence is discussed.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-10428832,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-10601205,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-10850985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-10920395,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-11073921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-11371529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-2822665,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-6498639,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-8349563,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-8405938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-8824616,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-9294428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11741876-9573157
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
184
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
327-30
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11741876-Agrobacterium tumefaciens,
pubmed-meshheading:11741876-Bacterial Outer Membrane Proteins,
pubmed-meshheading:11741876-Bacterial Proteins,
pubmed-meshheading:11741876-Datura stramonium,
pubmed-meshheading:11741876-Fimbriae, Bacterial,
pubmed-meshheading:11741876-Fimbriae Proteins,
pubmed-meshheading:11741876-Membrane Proteins,
pubmed-meshheading:11741876-Mutation,
pubmed-meshheading:11741876-Protein Precursors,
pubmed-meshheading:11741876-Protein Processing, Post-Translational,
pubmed-meshheading:11741876-Protein Sorting Signals,
pubmed-meshheading:11741876-Recombinant Proteins,
pubmed-meshheading:11741876-Serine Endopeptidases,
pubmed-meshheading:11741876-Virulence Factors
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pubmed:year |
2002
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pubmed:articleTitle |
Biogenesis of T pili in Agrobacterium tumefaciens requires precise VirB2 propilin cleavage and cyclization.
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pubmed:affiliation |
Davis Crown Gall Group, University of California, Davis, California 95616, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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