|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003374,
umls-concept:C0052430,
umls-concept:C0220781,
umls-concept:C0243072,
umls-concept:C0441655,
umls-concept:C0537284,
umls-concept:C0596448,
umls-concept:C0596973,
umls-concept:C0598129,
umls-concept:C1511636,
umls-concept:C1883254
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|
pubmed:issue |
26
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|
pubmed:dateCreated |
2001-12-19
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|
pubmed:abstractText |
Nucleophilic additions of lithium keto and ester enolates and mono- and bifunctional Grignard reagents to artemisitene provided C-16-derived artemisinin monomers, dimers, trimers, and tetramers whose antimalarial and cytotoxic activities have been evaluated.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
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pubmed:issn |
0022-2623
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
20
|
|
pubmed:volume |
44
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
4688-95
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11741486-Animals,
pubmed-meshheading:11741486-Antimalarials,
pubmed-meshheading:11741486-Antineoplastic Agents,
pubmed-meshheading:11741486-Artemisinins,
pubmed-meshheading:11741486-Cell Line,
pubmed-meshheading:11741486-Cercopithecus aethiops,
pubmed-meshheading:11741486-Crystallography, X-Ray,
pubmed-meshheading:11741486-Drug Screening Assays, Antitumor,
pubmed-meshheading:11741486-Humans,
pubmed-meshheading:11741486-Molecular Conformation,
pubmed-meshheading:11741486-Plasmodium falciparum,
pubmed-meshheading:11741486-Polymers,
pubmed-meshheading:11741486-Sesquiterpenes,
pubmed-meshheading:11741486-Structure-Activity Relationship,
pubmed-meshheading:11741486-Tumor Cells, Cultured
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pubmed:year |
2001
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pubmed:articleTitle |
C-16 artemisinin derivatives and their antimalarial and cytotoxic activities: syntheses of artemisinin monomers, dimers, trimers, and tetramers by nucleophilic additions to artemisitene.
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pubmed:affiliation |
Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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