Linked Life Data

11741103

Source:http://linkedlifedata.com/resource/pubmed/id/11741103

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-12-13
pubmed:abstractText
Several different mitochondrial DNA (mtDNA) sites for mutations of Leber's hereditary optic neuropathy (LHON) have been reported to be present in patients with multiple sclerosis (MS). To further study this association of LHON and MS in the Korean population, we tested 20 MS patients for the presence of mtDNA mutations at nucleotide (nt) 11778 in all 20 patients, and at nt 14484, nt 3460 and nt 15257 in 15, 12 and 12 patients, respectively. However, none of the MS patients exhibited any pathogenic LHON mtDNA mutations. In conclusion, we found no evidence for any association between MS and the LHON mutation in the Korean population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0030-3755
pubmed:author
pubmed:copyrightInfo
Copyright 2001 S. Karger AG, Basel
pubmed:issnType
Print
pubmed:volume
215
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
398-400
pubmed:dateRevised
2007-9-17
pubmed:meshHeading
pubmed:articleTitle
Leber's hereditary optic neuropathy mutations in Korean patients with multiple sclerosis.
pubmed:affiliation
Department of Ophthalmology, Seoul Municipal Boramae Hospital, Seoul National University College of Medicine, Seoul, Korea. hjm@snu.ac.kr
pubmed:publicationType
Journal Article