Numerous case reports have linked clozapine to the development of diabetes mellitus and hyperlipidemia in patients with schizophrenia. However, investigators have been unable to clearly demonstrate this association when compared with a control group receiving conventional antipsychotics.
Division of Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, 443 S Pharmacy Bldg, Iowa City, IA 52242-1112, USA. brian-lund@uiowa.edu