|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2001-12-12
|
|
pubmed:abstractText |
Accumulation of senile plaques containing amyloid beta (Abeta)-protein is a pathologic hallmark of Alzheimer disease. Amyloid beta-peptide is heterogeneous, with carboxyterminal variants ending at residues Val40 (Abetax-40), Ala42 (Abetax-42), or Thr43 (Abetax-43). The relative importance of each of these variants in dementia or cognitive decline remains unclear.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0003-9942
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
58
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2025-32
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:11735776-Aged,
pubmed-meshheading:11735776-Aged, 80 and over,
pubmed-meshheading:11735776-Alzheimer Disease,
pubmed-meshheading:11735776-Amyloid beta-Peptides,
pubmed-meshheading:11735776-Antibodies, Monoclonal,
pubmed-meshheading:11735776-Cognition Disorders,
pubmed-meshheading:11735776-Cross-Sectional Studies,
pubmed-meshheading:11735776-Disease Progression,
pubmed-meshheading:11735776-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:11735776-Female,
pubmed-meshheading:11735776-Humans,
pubmed-meshheading:11735776-Immunoelectrophoresis,
pubmed-meshheading:11735776-Immunohistochemistry,
pubmed-meshheading:11735776-Male,
pubmed-meshheading:11735776-Middle Aged,
pubmed-meshheading:11735776-Plaque, Amyloid,
pubmed-meshheading:11735776-Prefrontal Cortex,
pubmed-meshheading:11735776-Psychiatric Status Rating Scales
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline.
|
|
pubmed:affiliation |
Laboratory of Molecular Neuropsychiatry, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1230, New York, NY 10029, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
